Author
Washington University in St. LouisORCID 0000-0001-7698-3267Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Wentao Han, Hassan Bjeije, Hamza Celik…·Grant Anthony Challen
JARID2 inhibition enhances repopulating activity of human hematopoietic stem and progenitor cells in vivo via STAT1 upregulation.
Tyler M. Parsons, Aishwarya Krishnan, Infencia Xavier Raj…·Grant Anthony Challen
This study shows that leukemic clones can evolve independently of JAK2V617F in MPNs and contribute to disease progression through pro-inflammatory environments.
Kelly L. Bolton, Ryan N. Ptashkin, Teng Gao…·Elli Papaemmanuil
The paper shows oncologic therapy increases clonal hematopoiesis with DDR mutations, which predicts risk of therapy-related myeloid neoplasms.
Caroline J. Watson, Alana Papula, Yeuk P. G. Poon…·Jamie R. Blundell
The paper quantifies fitness advantages of pathogenic variants in clonal haematopoiesis using blood sequencing data from ~50,000 individuals.