Todd E. Druley

This study shows that KDM6A knockout in human iPSCs changes histone methylation at enhancers, leading to increased ectoderm gene expression.

The paper shows oncologic therapy increases clonal hematopoiesis with DDR mutations, which predicts risk of therapy-related myeloid neoplasms.

The paper quantifies fitness advantages of pathogenic variants in clonal haematopoiesis using blood sequencing data from ~50,000 individuals.