Katheryn Begg

This study shows ARID1A deficiency increases sensitivity to the G4 ligand pyridostatin due to impaired DNA repair, highlighting a role for ARID1A in G4 ligand-induced DNA damage responses.

This study identifies PBAF as a protector of centromere and pericentromere structure, showing that PBRM1 loss leads to centromere fragility and therapeutic vulnerability.

This study shows that Wnt signaling mediates mechanical strain responses during zebrafish joint development, affecting cell proliferation and migration but not chondrocyte intercalation.