Érika Kague

The paper characterizes lmx1b paralogues in zebrafish, revealing distinct roles in skeletal, kidney, and muscle development, and identifies a new role in notochord cell inflation.

This study genetically modifies zebrafish to demonstrate how altering individual traits can tune collective behavior, showing mutant fish exhibit more orderly motion than wildtype.

This study identifies 59 genome-wide significant loci for skull bone mineral density, including four novel loci, and links them to osteoporosis and craniofacial developmental defects.

The paper shows transformed notochordal cells in zebrafish cause skeletal damage, chronic wound-like responses, and bone homeostasis disruption, linking chordomas to inflammation and IVD degeneration.

This study identifies 15 genetic loci associated with muscle weakness in older adults through a large meta-analysis, revealing new pathways linked to aging and health outcomes.

The paper identifies NCOA3 as a candidate gene for autosomal dominant progressive hearing loss through linkage analysis and functional studies in zebrafish.

This study examines the effects of col11a2 loss in zebrafish on joint development and function, showing increased stiffness and early onset osteoarthritis.

This study shows that zebrafish lacking sp7 can replace teeth without attachment bone, but with poor differentiation and abnormal tooth orientation.

This study shows that Wnt signaling mediates mechanical strain responses during zebrafish joint development, affecting cell proliferation and migration but not chondrocyte intercalation.

This paper develops a zebrafish model to study joint dysplasia by manipulating the mechanical environment, identifying cellular factors that predict recovery of joint shape and function.