Author

Lillian Wu

Institute of Cancer ResearchORCID 0000-0003-3178-1770Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alison HarrodiD· 2 shared Jessica A. DownsiD· 2 shared Karen A. LaneiD· 2 shared Alan A. MelcheriD· 1 shared Andrea MusacchioiD· 1 shared Catherine NaughtoniD· 1 shared Claudio AlfieriiD· 1 shared Federica Schiavoni· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Alison HarrodORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintApr 13, 2026

CENP-B binds hairpin motifs in chromosome arms influencing gene expression

Lillian Wu, Karen A. Lane, Reyhan Muhammad…·Jessica A. Downs

This study identifies a non-centromeric role for CENP-B in binding hairpin motifs in chromosome arms, leading to dysregulated gene expression upon depletion.

2 citations

humanDNA methylation

𝕏 PostBluesky

Molecular BiologyNature CommunicationsPeer-reviewedFeb 26, 2025

PBRM1 directs PBAF to pericentromeres and protects centromere integrity

Karen A. Lane, Alison Harrod, Lillian Wu…·Jessica A. Downs

This study identifies PBAF as a protector of centromere and pericentromere structure, showing that PBRM1 loss leads to centromere fragility and therapeutic vulnerability.

10 citations

humanexperimental assay

𝕏 PostBluesky