Author

Pierre Larraufie

University of CambridgeORCID 0000-0001-7718-6200Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Fiona Mary GribbleiD· 2 shared Frank M. ReimanniD· 2 shared A. VaugrenteiD· 1 shared Alexandra Willemetz· 1 shared Anne E. WhiteiD· 1 shared Bas BrouwersiD· 1 shared Brandon LeeiD· 1 shared Claire GaudichoniD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

Fiona Mary GribbleORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 2, 2026

Non-canonical signaling mechanisms of short-chain fatty acid receptors in glucagon-like peptide-1 (GLP-1) releasing enteroendocrine cells

Karly E. Masse, Brandon Lee, HengLiang Wu…·Van B. Lu

This study investigates how FFA2 and FFA3 activation in enteroendocrine cells affects GLP-1 secretion through non-canonical signaling pathways.

DOI 10.64898/2026.03.01.708924

mousebulk RNA-seq

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PhysiologybioRxivPreprintFeb 24, 2024

Development of rat organoids to study intestinal adaptations after Roux-en-Y Gastric Bypass

Soukaïna Benhaddou, Lara Ribeiro‐Parenti, A. Vaugrente…·Pierre Larraufie

This study develops a protocol for growing rat small intestine organoids and finds no significant differences in organoid size or gene expression between RYGB and Sham-operated rats.

1 citation

ratorganoid / primary culture

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NeuroscienceMolecular MetabolismPeer-reviewedAug 21, 2018

Human POMC processing in vitro and in vivo revealed by quantitative peptidomics

Peter Kirwan, Richard G. Kay, Bas Brouwers…·Florian T. Merkle

The paper identifies β-MSH and desacetyl-MSH as major POMC-derived peptides in human hypothalamic neurons, suggesting their underappreciated role in obesity.

31 citations

humanproteomics

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