Alejandro Schcolnik‐Cabrera

This study shows eIF4A inhibition disrupts resistance mechanisms in BRAF-mutant melanoma by targeting translational and metabolic programs, improving tumor control when combined with BRAF inhibitors.

This study investigates the role of YAP/TAZ in dendritic cell-mediated pathogenesis of insulin resistance and NAFLD using a high-fat diet model, finding minimal impact on disease progression.

This study shows that impairing Rasal1 enhances T cell antitumor immunity and improves responses to PD-1 therapy in melanoma.

This study shows FOXK1 O-GlcNAcylation regulates the E2F pathway, promoting cell proliferation and oncogenesis by modulating chromatin structure and transcriptional activity.

This study shows that low-dose genistein combined with chemotherapy reduces breast cancer cell viability and migration by altering metabolic pathways, particularly fatty acid metabolism.

The paper investigates how maternal immune dysregulation and dysbiosis affect offspring gut immune homeostasis and T1D development in NOD mice.