Author

Ariana Vargas‐Castillo

Harvard UniversityORCID 0000-0003-3239-6022Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

Abhilash JayarajiD· 1 shared Alejandro Schcolnik‐CabreraiD· 1 shared Alma Delia Chávez-BlancoiD· 1 shared Andrea ArmaniiD· 1 shared Anna M. PuszynskaiD· 1 shared Armando Roberto TovariD· 1 shared Birgitta A. RybackiD· 1 shared Bruce M. SpiegelmaniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Abhilash JayarajORCID

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2 papers

Recent·Most cited

Cancer BiologyLife SciencesPeer-reviewedMar 14, 2025

Metabolic reprogramming and synergistic cytotoxicity of genistein and chemotherapy in human breast cancer cells

Sandra Tobón‐Cornejo, Ariana Vargas‐Castillo, Mandy Juárez…·Alejandro Schcolnik‐Cabrera

This study shows that low-dose genistein combined with chemotherapy reduces breast cancer cell viability and migration by altering metabolic pathways, particularly fatty acid metabolism.

9 citationstop 4%

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintApr 10, 2024

Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST

Hans‐Georg Sprenger, Melanie J. Mittenbühler, Yizhi Sun…·Bruce M. Spiegelman

This study identifies MPST as the direct target of EGT, showing it enhances mitochondrial respiration and exercise performance in mice.

7 citations

mouseproteomics

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