Antonio Carlos Bianco

This study shows thyroid hormone promotes fetal neurogenesis by inducing transcriptional changes in neural precursor cells, highlighting the importance of maternal thyroid hormone levels for brain development.

This study shows overnutrition causes hypothyroidism in mice by impairing thyroid hormone biosynthesis and utilization, despite thyroid adaptations, and finds a link between BMI and thyroid vascularization in humans.

The paper identifies a neuronal pathway for T3 transport and signaling in the brain that explains variable L-T4 therapy effectiveness and resolves the paradox of T3 signaling amid high D3 activity.

The paper identifies 14 genes involved in osteoarthritis using mutant mice and validates their role through functional studies and genome editing.