PhysiologybioRxivPreprint
Overnutrition directly impairs thyroid hormone biosynthesis and utilization, causing hypothyroidism, despite remarkable thyroidal adaptations
Jessica Rampy, Alejandra Paola Torres-Manzo, Kendra Hoffsmith…·Nancy Carrasco
This study shows overnutrition causes hypothyroidism in mice by impairing thyroid hormone biosynthesis and utilization, despite thyroid adaptations, and finds a link between BMI and thyroid vascularization in humans.
DOI 10.1101/2025.03.31.645596