Author

Bärbel Finkenstädt

University of WarwickORCID 0000-0001-7754-1380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam Michael JohanseniD· 1 shared Daniel HebenstreitiD· 1 shared James Teahan· 1 shared Måns UnossoniD· 1 shared Marco BrancaccioiD· 1 shared Mark D. WalshiD· 1 shared Massimo CavallaroiD· 1 shared Matt JonesiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Adam Michael JohansenORCID

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2 papers

Recent·Most cited

Systems BiologyPLoS Computational BiologyPeer-reviewedDec 17, 2021

A spatio-temporal model to reveal oscillatorphenotypes in molecular clocks: Parameterestimation elucidates circadian gene transcriptiondynamics in single-cells

Måns Unosson, Marco Brancaccio, Michael Harvey Hastings…·Bärbel Finkenstädt

The paper develops a spatio-temporal model to analyze circadian gene expression dynamics in single cells, revealing spatial and temporal differences in oscillation robustness and regulatory profiles in mouse SCN tissue.

3 citations

mousebulk RNA-seq

𝕏 PostBluesky

Systems BiologyGenome biologyPeer-reviewedFeb 4, 2021

3'-5' crosstalk contributes to transcriptional bursting

Massimo Cavallaro, Mark D. Walsh, Matt Jones…·Daniel Hebenstreit

The paper measures transcriptional bursting using Bayesian methods and shows that polymerase shuttling affects burst size and frequency, with implications for transcriptional noise.

30 citations

humanChIP-seq

𝕏 PostBluesky