Cell BiologyJCI InsightPeer-reviewed
ERK hyperactivation in epidermal keratinocytes impairs intercellular adhesion and drives Grover disease pathology
Cory L. Simpson, Afua Tiwaa, Shivam A. Zaver…·Johann Eli Gudjonsson
This study shows ERK hyperactivation in keratinocytes causes impaired adhesion and drives Grover disease, supporting MEK inhibition as a potential therapy.
12 citations