Author

Efrosini Kokkoli

Johns Hopkins UniversityORCID 0000-0001-7783-0158Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam G. SchrumiD· 1 shared Bret D. UleryiD· 1 shared Brett T Rygelski· 1 shared Brittany N. AlleniD· 1 shared Clark C. CheniD· 1 shared Eric Wong· 1 shared Gatikrushna SinghiD· 1 shared Gracen F. Seim· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

Adam G. SchrumORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 22, 2025

Modulating populational variance of methyl-guanine methyl transferase expression through miR-181d degradation: a novel mechanism of temozolomide resistance

Gatikrushna Singh, Shilpi Singh, Iteeshree Mohapatra…·Clark C. Chen

The paper shows that miR-181d degradation via a PNPT1-ATR feed-forward loop increases MGMT expression variance, leading to temozolomide resistance in glioblastoma cells.

DOI 10.1101/2025.04.22.650094

humanbulk RNA-seq

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BioengineeringbioRxivPreprintJun 10, 2024

Adjuvant Delivery Method and Nanoparticle Charge Influence Peptide Amphiphile Micelle Vaccine Bioactivity

Rui Zhang, Brett T Rygelski, Luke E. Kruse…·Bret D. Ulery

This study investigates how adjuvant delivery methods and nanoparticle charge affect the bioactivity of peptide amphiphile micelle vaccines, showing improved dendritic cell activation with electrostatic complexation.

1 citation

experimental assayhost-pathogen & immune response

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