Cell BiologyThe Journal of Cell BiologyPeer-reviewed
Structural basis for recognition of unfolded proteins by the ER stress sensor ERN1/IRE1α
Mariska S. Simpson, Heidi E. De Luca, Sarah Cauthorn…·Wayne I. Lencer
This study identifies a 7-residue motif in unfolded proteins recognized by IRE1LD, revealing how IRE1 detects misfolded proteins to trigger the UPR.
10 citations