Kai Xue

This study determines the bilayer-bound structure of SARS-CoV-2 E protein in complex with a host PDZ domain, revealing its pentameric oligomer state and structural interactions.

This paper shows that anle138b binds to a cavity in lipidic Aβ fibrils and reduces fibril formation by 75%, suggesting a potential therapeutic mechanism for Alzheimer's disease.

The paper investigates the transmembrane signaling mechanism of the CitA histidine kinase using structural biology techniques and shows how structural changes in the sensor domain are transmitted across the membrane.