Author

Jorge Diogo Da Silva

University of MinhoORCID 0000-0001-7863-0406Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Andreia Teixeira‐CastroiD· 2 shared Liliana Meireles-Costa· 2 shared Patrı́cia MacieliD· 2 shared Ana Luı́sa CarvalhoiD· 1 shared Andreia Neves‐CarvalhoiD· 1 shared Beatriz RodriguesiD· 1 shared Bruna Ferreira-LombaiD· 1 shared Bruno AlmeidaiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Andreia Teixeira‐CastroORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJan 24, 2026

PRO-FitS: a novel phenotypic assay to identify enhancers of proteostasis in C. elegans

Daniela Vilasboas‐Campos, Jorge H. Fernandes, M. C. M. M. Michelle Cristina Magalhàes Melgaço Costa Costa…·Andreia Teixeira‐Castro

This paper introduces PRO-FitS, a C. elegans-based phenotypic assay to identify proteostasis enhancers, validated through mTOR inhibition and serotonergic signaling effects on heat shock-induced proteotoxicity.

DOI 10.64898/2026.01.22.701023

C. elegansexperimental assay

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NeurosciencebioRxivPreprintJul 15, 2022

Regulation of neuronal mRNA splicing and Tau isoform ratio by ATXN3 through deubiquitylation of splicing factors

Andreia Neves‐Carvalho, Sara Duarte‐Silva, Joana Margarida Silva…·Patrı́cia Maciel

This study identifies ATXN3's role in regulating neuronal mRNA splicing and Tau isoform ratio through deubiquitylation of splicing factors, linking it to SCA3 pathology.

3 citations

humanbulk RNA-seq

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