Daniela Vilasboas‐Campos

The paper identifies valence-specific neuronal ensembles in the laterodorsal tegmentum that encode salient stimuli and modulate motivated behavior through optogenetic reactivation.

The paper identifies distinct neuronal ensembles in the nucleus accumbens activated by cocaine and foot shock, showing different functional roles in reward and aversion.

This paper introduces PRO-FitS, a C. elegans-based phenotypic assay to identify proteostasis enhancers, validated through mTOR inhibition and serotonergic signaling effects on heat shock-induced proteotoxicity.

This study shows that CLR01, a supramolecular tweezer, reduces Atx3 aggregation by binding to a specific site, delaying fibril formation and improving symptoms in SCA3 models.

This study evaluates NLX-112, a 5-HT1A receptor agonist, in a mouse model of SCA3, showing improved motor function and neuroprotection when administered pre-symptomatically.

This study shows that cocaine-induced changes in cholinergic projections from the LDT to the NAc bidirectionally affect cocaine's reinforcing effects.

This study identifies dopamine and catecholamines as inhibitors of Atx3 aggregation, suggesting potential use of dopaminergic drugs for MJD treatment.