Author
University of MinhoORCID 0000-0002-5710-0040Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
3 papers
Recent·Most cited
Alexandra Silva, Sara Duarte‐Silva, Pedro Miguel Martins…·Sandra Macedo‐Ribeiro
This study shows that CLR01, a supramolecular tweezer, reduces Atx3 aggregation by binding to a specific site, delaying fibril formation and improving symptoms in SCA3 models.
Andreia Neves‐Carvalho, Sara Duarte‐Silva, Joana Margarida Silva…·Patrı́cia Maciel
This study identifies ATXN3's role in regulating neuronal mRNA splicing and Tau isoform ratio through deubiquitylation of splicing factors, linking it to SCA3 pathology.
Kristin Mayoral-Palarz, Andreia Neves‐Carvalho, Sara Duarte‐Silva…·Kamran Khodakhah
This study shows that in a mouse model of SCA3, abnormal cerebellar output occurs early, before visible neuronal damage, and may be a target for therapy.