Gerburg M. Wulf

Latent Dirichlet allocation topics from hydrogel-array spatial miRNA maps of day-10 treated K14-Cre Brca1/Trp53 mouse breast tumors separated olaparib-sensitive (miR-21-dominated) from resistant (let-7a-dominated) tumors.

The paper estimates the timing of homologous recombination deficiency (HRD) onset in breast cancers using HRDTimer, finding HRD occurs years before diagnosis in different subtypes.

This paper develops chemotherapy-specific predictors for triple-negative breast cancer using patient-derived xenografts and multi-omic data, achieving high AUROC scores for response prediction.