Chen Lu Huang

ProteoformTracker models MS signals and evaluates proteoform detectability in top-down and middle-down proteomics for experimental planning.

This paper develops chemotherapy-specific predictors for triple-negative breast cancer using patient-derived xenografts and multi-omic data, achieving high AUROC scores for response prediction.

This study shows that Myt transcription factors prevent over-activation of stress-response genes in pancreatic β cells, maintaining their function and survival.