Angelo Solania

This study identifies isopentenyladenine as a secreted metabolite from Faecalibacterium prausnitzii that modulates host immune responses and mitigates gut inflammation in murine models.

The paper designs and characterizes non-hydrolyzable peptidomimetic inhibitors to selectively probe caspase-7 over caspase-3 by exploiting differences in their prime-side active-site architecture.