Author

Laurent Potvin-Trottier

Concordia UniversityORCID 0000-0001-7876-2820Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alexander D. Naydich· 1 shared Alice HongiD· 1 shared Andreas HilfingeriD· 1 shared Andrew A VerdegaaliD· 1 shared Carolina TropiniiD· 1 shared David RichmondiD· 1 shared David T. RiglariD· 1 shared Emanuele LeonciniiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperSynthetic Biology

Alexander D. Naydich

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Systems BiologyeLifePeer-reviewedDec 16, 2025

Exploiting fluctuations in gene expression to detect causal interactions between genes

Euan Joly-Smith, Mir Mikdad Talpur, Paige Allard…·Andreas Hilfinger

This paper introduces a method to detect causal gene interactions using natural expression fluctuations in genetically identical cells, validated in E. coli synthetic circuits.

DOI 10.7554/elife.92497

E. colibulk RNA-seq

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintMar 18, 2025

Expanding the Bacteroides synthetic biology toolkit to develop an in vivo intestinal malabsorption biosensor.

Giselle McCallum, Juan C. Burckhardt, Jerry He…·Carolina Tropini

The paper expands genetic tools for Bacteroides thetaiotaomicron to create biosensors for detecting gut malabsorption through fluorescence-based environmental sensing.

DOI 10.1101/2025.03.18.644028

mouseexperimental assay

𝕏 PostBluesky

Synthetic BiologyNature CommunicationsPeer-reviewedOct 11, 2019

Variability of bacterial behavior in the mammalian gut captured using a growth-linked single-cell synthetic gene oscillator

David T. Riglar, David Richmond, Laurent Potvin-Trottier…·Pamela A. Silver

This study uses a synthetic gene oscillator to analyze bacterial growth dynamics in the gut under healthy and inflammatory conditions, revealing variability in single-cell behavior.

50 citations

mouseproteomics

𝕏 PostBluesky