David T. Riglar

The paper identifies gut microbiome microproteins that modulate host metabolism using a whole-organism screening platform in C. elegans.

This paper introduces a dual-view oblique plane microscope for high-resolution imaging of thick cleared tissue samples across multiple species.

The paper uses engineered bacterial biosensors to measure sialic acid availability in the inflamed mouse gut, revealing spatial and temporal variations linked to inflammation.

The paper develops a platform to identify inducible biosensors from microbial sources, demonstrating its ability to find novel sensors responsive to inflammatory conditions in the gut.

This study uses a synthetic gene oscillator to analyze bacterial growth dynamics in the gut under healthy and inflammatory conditions, revealing variability in single-cell behavior.

The paper engineers inter-species amino acid cross-feeding in bacterial consortia to increase population evenness in synthetic microbial communities.

The paper develops a synthetic gene circuit system to identify in vivo-responsive biosensors in gut bacteria, demonstrating their utility in both healthy and inflamed gut environments.