Kamran Khodakhah

This study demonstrates that cerebellar projections to the substantia nigra pars compacta form monosynaptic glutamatergic synapses that modulate dopamine levels and behavior.

This study shows that in a mouse model of SCA3, abnormal cerebellar output occurs early, before visible neuronal damage, and may be a target for therapy.

This study shows that reducing Csf3 in Csf1r+/- mice improves anxiety, motor coordination, and social interaction but not cognitive deficits, and reduces microglial activation in the cerebellum.

This study shows that including vascular cells with neural precursor cells improves graft survival and vascularization after stroke.

This study uses acute cerebellar knockdown of Sgce in mice to replicate key features of DYT11, including dystonia and ethanol-responsive myoclonus.