Author

Valeria Ghezzi

Linköping UniversityORCID 0000-0001-7908-0792Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Amaia Jauregi‐MigueliD· 2 shared Anna NordiniD· 2 shared Claudio CantùiD· 2 shared Gianluca ZambaniniiD· 2 shared Pierfrancesco PagellaiD· 2 shared Simon SöderholmiD· 2 shared Alessandro Mattia· 1 shared Andreas E. MooriD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersDevelopmental Biology

Amaia Jauregi‐MiguelORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

The Developmental Transcription Factor TBX3 Physically Engages with the Wnt/β-catenin Transcriptional Complex in Human Colorectal Cancer Cells to Regulate Metastasis Genes

Amaia Jauregi‐Miguel, Simon Söderholm, Tamina Weiss, Anna Nordin, Valeria Ghezzi, Salome M. Brütsch, Pierfrancesco Pagella, Yorick Bernardus Cornelis van de Grift, Gianluca Zambanini, Jacopo Ulisse, Alessandro Mattia, Ruslan M. Deviatiiarov, Elena Faustini, Lavanya Moparthi, Francisca Lottersberger, , Claudio Cantù

This study identifies TBX3 as a functional component of the Wnt/β-catenin complex in human colorectal cancer, showing it modulates metastasis-related transcription through direct protein interactions.

bioRxiv · Dec 18, 2023 · PreprintDevelopmental Biology

Single-cell response to Wnt activation in human embryonic stem cells reveals uncoupling of Wnt target gene expression

Simon Söderholm, Amaia Jauregi‐Miguel, Pierfrancesco Pagella, Valeria Ghezzi, Gianluca Zambanini, Anna Nordin, Claudio Cantù

The paper examines single-cell Wnt signaling responses in human embryonic stem cells and finds that Wnt target gene activation varies among cells, showing uncoupling in gene expression patterns.

bioRxiv · Jan 11, 2023 · PreprintDevelopmental Biology