Susan E. Leggett

The paper shows that ligand endocytosis enhances directional information in cell-cell attraction by reshaping extracellular gradients.

The paper shows partial EMT enables collective migration through collision guidance in heterogeneous cell populations, revealing emergent tissue-level behaviors.

The paper investigates how high-fat circulating nutrients affect tumor growth and invasion in a 3D microfluidic model of triple-negative breast cancer, finding increased metabolic activity and MMP1 expression.

This paper introduces a method to rapidly fabricate PDMS-based organ-on-a-chip devices using 3D printing and epoxy coatings, enabling accessible and scalable microfluidic systems for biological applications.