Author

Qiao Mao

Leiden University Medical CenterORCID 0000-0001-7938-6660Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Ahmed Essam MahfouziD· 2 shared Annemieke M Aartsma-RusiD· 2 shared Laura G.M. HeezeniD· 2 shared Maaike van PutteniD· 2 shared Pietro SpitaliiD· 2 shared Sharon I. de Vries· 2 shared Alireza Ahmadi· 1 shared Aurélie GoyenvalleiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersNeuroscience

Ahmed Essam MahfouzORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintOct 19, 2026

Spatial transcriptomics maps region and isoform specific brain alterations in mdx and mdx4cv models of Duchenne muscular dystrophy

Qiao Mao, Laura G.M. Heezen, Sharon I. de Vries…·Ahmed Essam Mahfouz

This study uses spatial transcriptomics to compare gene expression changes in brain regions of mdx and mdx4cv DMD mouse models, revealing distinct patterns linked to dystrophin isoform loss.

DOI 10.64898/2026.10.13.758478

mousespatial transcriptomics

𝕏 PostBluesky

NeuroscienceiSciencePeer-reviewedJul 23, 2026

Evaluating exon-skipping therapies targeting the central nervous system in Duchenne muscular dystrophy using high-resolution spatial transcriptomics

Qirong Mao, Alireza Ahmadi, Sharon I. de Vries…·Pietro Spitali

This study uses spatial transcriptomics to evaluate exon-skipping therapies for DMD in the CNS, showing U7ex51 effectively restores full-length dystrophin isoforms in neurons.

DOI 10.1016/j.isci.2026.116906

mousespatial transcriptomics

𝕏 PostBluesky