Author

Luca Zanella

Columbia UniversityORCID 0000-0001-7955-0168Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Alessandro VasciaveoiD· 2 shared Alexander L.E. WangiD· 2 shared Andrea CalifanoiD· 2 shared Aziz ZafariD· 1 shared Biyun ZhengiD· 1 shared Bryana R. BeliniD· 1 shared Chandan GuhaiD· 1 shared Chia‐Wei ChengiD· 1 shared

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2024-2024 · peak 2/yr

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10 top collaborators · 39 mutual co-author links

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2 shared papersBioinformatics

Alessandro VasciaveoORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintAug 25, 2024

pyVIPER: A fast and scalable Python package for rank-based enrichment analysis of single-cell RNASeq data

Alexander L.E. Wang, Zizhao Lin, Luca Zanella…·Alessandro Vasciaveo

pyVIPER is a Python package for fast, scalable rank-based enrichment analysis of scRNA-seq data, offering significant runtime improvements over VIPER for large datasets.

2 citations

scRNA-seqstatistical model

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Developmental BiologyCellPeer-reviewedJun 1, 2024

Isthmus progenitor cells contribute to homeostatic cellular turnover and support regeneration following intestinal injury

Ermanno Malagola, Alessandro Vasciaveo, Yosuke Ochiai…·Timothy Cragin Wang

This study challenges the traditional model of intestinal stem cells by showing that Lgr5+ cells are not the sole stem cell compartment and that stemness exists in the isthmus region, contributing to homeostasis and regeneration.

95 citationstop 1%

mousescRNA-seq

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