Cancer BiologyCancer Research CommunicationsPeer-reviewed
CD4+ T-cells sensitize quasi-mesenchymal breast tumors lacking CD73 to anti-CTLA4 immune checkpoint blockade therapy
Shiney Chandraganti, Caitlyn Sams, Sarthak Sahoo…·Anushka Dongre
This study shows that targeting CD73 in quasi-mesenchymal breast tumors enhances their response to anti-CTLA4 therapy through CD4+ T-cell dependence.
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