Kimaya M. Bakhle

The paper shows that in mixed E-qM breast tumors, qM cancer cells create immunosuppressive niches leading to MHC-I downregulation and immune evasion.

This study examines feline mammary carcinomas and finds they exhibit stemness, epithelial-mesenchymal plasticity, and M2-like macrophage infiltration, similar to human triple-negative breast cancer.

This study shows that targeting CD73 in quasi-mesenchymal breast tumors enhances their response to anti-CTLA4 therapy through CD4+ T-cell dependence.

This study shows that epithelial-mesenchymal plasticity in canine mammary carcinomas is linked to immunosuppressive features and recruitment of immunosuppressive cells.

The paper investigates how active histone methylation marks, specifically H3K4me3 and H3K36me3, change with age in Drosophila photoreceptors and their impact on splicing and visual function.

This study identifies Clock and cycle as neuroprotective circadian regulators in Drosophila photoreceptors that prevent retinal degeneration and oxidative stress during aging.

The paper develops a method to profile chromatin states in specific Drosophila cell types using GFP-tagged nuclei and applies it to photoreceptor neurons.