Author

Corina Simian

Northeastern UniversityORCID 0009-0004-4074-2428Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Anushka DongreiD· 1 shared Brian D. RuddiD· 1 shared Brian FengiD· 1 shared Caitlyn SamsiD· 1 shared George W. BelliD· 1 shared Isabel O’ConnelliD· 1 shared Kimaya M. BakhleiD· 1 shared Lynna LiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Anushka DongreORCID

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1 paper

Recent·Most cited

CD4+ T-cells sensitize quasi-mesenchymal breast tumors lacking CD73 to anti-CTLA4 immune checkpoint blockade therapy

Shiney Chandraganti, Caitlyn Sams, Sarthak Sahoo, Brian Feng, Isabel O’Connell, Lynna Li, Sunita Nepal, Siddhartha Pulukuri, Kimaya M. Bakhle, Prathapan Thiru, Corina Simian, Viviana Maymi, Brian D. Rudd, George W. Bell, Stephen Hatfield, , Anushka Dongre

This study shows that targeting CD73 in quasi-mesenchymal breast tumors enhances their response to anti-CTLA4 therapy through CD4+ T-cell dependence.

Cancer Research Communications · May 12, 2026Peer-reviewedCancer Biology