Author

Sean J. Johnson

Utah State UniversityORCID 0000-0001-7992-2494Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Organism:yeast· 1

Frequent Co-Authors

Joshua M. DensoniD· 2 shared Alvan C. HenggeiD· 1 shared Darby BalliD· 1 shared Dariia YehorovaiD· 1 shared Eric A. GaucheriD· 1 shared J. Patrick LoriaiD· 1 shared José M. Sánchez‐RuiziD· 1 shared Kayla Thompson· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Joshua M. DensonORCID

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2 papers

Recent·Most cited

BiochemistryJACS AuPeer-reviewedDec 10, 2025

Conformational Dynamics and Catalytic Backups in a Hyper-Thermostable Engineered Archaeal Protein Tyrosine Phosphatase

Dariia Yehorova, Nikolas Alansson, Ruidan Shen…·Shina Caroline Lynn Kamerlin

This paper describes an engineered archaeal PTP with enhanced thermostability and unique biochemical properties, revealing insights into enzyme evolution and biotechnological potential.

DOI 10.1021/jacsau.5c00756

protein structureexperimental assay

𝕏 PostBluesky

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedJan 3, 2025

TRAMP assembly alters the conformation and RNA binding of Mtr4 and Trf4-Air2

Joshua M. Denson, Naifu Zhang, Darby Ball…·Sheena D’Arcy

This study investigates how TRAMP complex assembly affects RNA binding and conformation of Mtr4 and Trf4-Air2 in yeast, revealing dynamic changes in RNA recognition motifs and binding sites.

2 citations

yeastexperimental assay

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