Author

Eric A. Gaucher

Georgia State UniversityORCID 0000-0001-6836-0828Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Eric A. Gaucher1 paper

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Approach:biophysical modeling· 1 Organism:plant (other)· 1 Approach:statistical model· 1

Frequent Co-Authors

José M. Sánchez‐RuiziD· 2 shared Nuria Ramirez MolinaiD· 2 shared Shina Caroline Lynn KamerliniD· 2 shared Valeria A. RissoiD· 2 shared Alvan C. HenggeiD· 1 shared Andrea M. ChániqueiD· 1 shared Bernhard LolliD· 1 shared Bruno Di GeronimoiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

José M. Sánchez‐RuizORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedAug 14, 2026

Deciphering the evolutionary origin of the stereoselectivity of short-chain dehydrogenases in the oxidation of the monoterpenol 1-borneol

Jasmin Zuson, Carl P. O. Helmer, Bruno Di Geronimo…·Robert Kourist

The paper investigates how natural evolution creates enantioselectivity in plant borneol dehydrogenases through ancestral sequence reconstruction and simulations.

DOI 10.1038/s41467-026-76435-1

plant (other)protein structure

𝕏 PostBluesky

BiochemistryJACS AuPeer-reviewedDec 10, 2025

Conformational Dynamics and Catalytic Backups in a Hyper-Thermostable Engineered Archaeal Protein Tyrosine Phosphatase

Dariia Yehorova, Nikolas Alansson, Ruidan Shen…·Shina Caroline Lynn Kamerlin

This paper describes an engineered archaeal PTP with enhanced thermostability and unique biochemical properties, revealing insights into enzyme evolution and biotechnological potential.

DOI 10.1021/jacsau.5c00756

protein structureexperimental assay

𝕏 PostBluesky

Molecular BiologyMolecular Biology and EvolutionPeer-reviewedMay 26, 2023

Protection of catalytic cofactors by polypeptides as a driver for the emergence of primordial enzymes

Luis I. Gutierrez-Rus, Gloria Gamiz-Arco, José Antonio Gavira…·José M. Sánchez‐Ruiz

The paper identifies heme protection by polypeptides as a mechanism enhancing catalytic efficiency in ancestral proteins, suggesting it may have driven the evolution of enzymes.

7 citations

experimental assay

𝕏 PostBluesky