Author

Alvan C. Hengge

Utah State UniversityORCID 0000-0002-5696-2087Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

José M. Sánchez‐RuiziD· 2 shared Shina Caroline Lynn KamerliniD· 2 shared Andrej BergiD· 1 shared Andrey O. DemkiviD· 1 shared Antonietta ParracinoiD· 1 shared Dariia YehorovaiD· 1 shared Encarnación Medina‐CarmonaiD· 1 shared Eric A. GaucheriD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

José M. Sánchez‐RuizORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Conformational Dynamics and Catalytic Backups in a Hyper-Thermostable Engineered Archaeal Protein Tyrosine Phosphatase

Dariia Yehorova, Nikolas Alansson, Ruidan Shen, Joshua Denson, Michael Robinson, Valeria A. Risso, Nuria Ramirez Molina, J. Patrick Loria, Eric A. Gaucher, José M. Sánchez‐Ruiz, Alvan C. Hengge, Sean J. Johnson, Shina Caroline Lynn Kamerlin

This paper describes an engineered archaeal PTP with enhanced thermostability and unique biochemical properties, revealing insights into enzyme evolution and biotechnological potential.

JACS Au · Dec 10, 2025Peer-reviewedBiochemistry

Redefining the Limits of Functional Continuity in the Early Evolution of P-Loop NTPases

Andrey O. Demkiv, Saacnicteh Toledo‐Patiño, Encarnación Medina‐Carmona, Andrej Berg, Gaspar Pinto, Antonietta Parracino, José M. Sánchez‐Ruiz, Alvan C. Hengge, Paola Laurino, Liam M. Longo, Shina Caroline Lynn Kamerlin

This paper challenges the evolutionary model that the Walker A motif was a seed for early P-loop NTPases by showing that disembodied Walker A peptides do not form stable phosphate-binding nests.

Molecular Biology and Evolution · Mar 11, 2025Peer-reviewedBiophysics