Alin Rai

The paper develops a human cardiac microtissue model to study ischemia-reperfusion injury and shows that nanovesicles improve cardiomyocyte survival and function through proteomic changes.

This paper develops a dual-omics workflow to map subcellular proteome and lipidome in mouse heart, revealing sex-dependent molecular differences and conserved subcellular lipid features.

This paper develops an adhesive silk hydrogel patch for localized and sustained delivery of stem cell-derived nanovesicles, showing anti-fibrotic effects in vitro and in a mouse model.

The paper identifies hallmark protein and lipid features of circulating extracellular vesicles in humans using multi-omics analysis and provides an open-source tool for further exploration.

This study identifies proteomic changes in midbody remnants (MBRs) from MDCK cells and H-Ras-transformed cells during EMT, revealing distinct protein profiles associated with mesenchymal and epithelial states.