Author
Adelaide UniversityORCID 0000-0001-7999-1385Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Stephanie A. Nguyen, Isis Pinner, C. Ruth Wang…·John B. Bruning
This paper characterizes the structure and inhibition of mannitol-2-dehydrogenase in Aspergillus fumigatus, identifying 1,4-benzoquinone as a potent inhibitor with antifungal activity.
Isis Pinner, Isabel N. Schultz, Jordan L. Pederick…·John B. Bruning
This study characterizes the structure and catalytic mechanism of AfuCys1a, identifies potential inhibitors, and aims to combat antifungal drug resistance in Aspergillus fumigatus.
Daniel P. McDougal, Jordan L. Pederick, Scott J. Novick…·John B. Bruning
The paper identifies a ternary switch in ERα LBD that regulates receptor activity through distinct H12 conformations, revealing an apo state and its destabilization by mutations.