Pasquale Valenzisi

The paper shows that low-dose DNA replication perturbation in fibroblasts triggers a secretory response and bystander effect without DNA damage.

This study identifies a WRNIP1-ATM-FANCJ pathway that resolves G-quadruplexes by stabilizing FANCJ, preventing genome instability.

This study identifies phosphorylation events on WRN that regulate end-resection and RAD51-mediated repair at replication forks.