Author

Pietro Pichierri

Istituto Superiore di SanitàORCID 0000-0002-2702-3523Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Annapaola FranchittoiD· 3 shared Benedetta Perdichizzi· 2 shared Floriana CappielloiD· 2 shared Pasquale ValenzisiiD· 2 shared Alfredo PagliucaiD· 1 shared Apurva Tadimari PrabhakariD· 1 shared Austin Witt· 1 shared Aya H. Youssef· 1 shared

Activity by Year

2026-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersCell Biology

Annapaola FranchittoORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A novel imaging biosensor for the detection of reversed replication forks and four-way junctions in human cells

Eva Malacaria, Elena Roscioli, Annapaola Franchitto, Pietro Pichierri

The paper introduces a biosensor to detect reversed replication forks and four-way junctions in human cells, enabling spatial analysis of DNA structures in situ.

bioRxiv · Aug 24, 2026 · PreprintCell Biology

Subthreshold perturbation of DNA replication induces a secretory response and a bystander effect in naïve human fibroblasts

Benedetta Perdichizzi, Floriana Cappiello, Flavia Di Feo, Loredana Le Pera, Alfredo Pagliuca, Pasquale Valenzisi, Marco Rosina, Daniela Merlo, Annapaola Franchitto, Pietro Pichierri

The paper shows that low-dose DNA replication perturbation in fibroblasts triggers a secretory response and bystander effect without DNA damage.

bioRxiv · Aug 21, 2026 · PreprintCell Biology

WRNIP1-ATM signaling promotes G-quadruplex resolution by preserving FANCJ stability

Pasquale Valenzisi, Rosa Parrillo, Pietro Pichierri, Annapaola Franchitto

This study identifies a WRNIP1-ATM-FANCJ pathway that resolves G-quadruplexes by stabilizing FANCJ, preventing genome instability.

bioRxiv · Jul 3, 2026 · PreprintCell Biology

HPV16 recruitment of SMARCAL1 to viral and host replication forks is required for the viral life cycle

Claire D. James, Aya H. Youssef, Jenny D Roe, Floriana Cappiello, Francesca Antonella Aiello, Benedetta Perdichizzi, Rachel L. Lewis, Austin Witt, Apurva Tadimari Prabhakar, Xu Wang, Molly L. Bristol, Pietro Pichierri, Iain M. Morgan

This paper shows that HPV16 requires SMARCAL1 to recruit to viral and host replication forks, which is essential for its life cycle and prevents DNA damage and genome integration.

mBio · Mar 30, 2026Peer-reviewedMicrobiology