Andrew S. Moore

The paper shows that mitochondrial DNA nucleoid distribution is controlled by pearling and cristae structure, revealing a mechanism for nucleoid spacing and segregation.

This paper shows RNA-seq can detect most mutations found by WGS in pediatric tumors and provides additional insights into their pathogenicity.

This study shows asciminib effectively treats NUP214::ABL1 ALL in preclinical models by inhibiting ABL1 kinase and improving survival.

The paper develops a targeted sequencing panel for paediatric solid tumours and validates its sensitivity and specificity across various sample types.