Author

Damian Lozano

The University of Texas at San Antonio Health Science CenterORCID 0000-0001-8078-7912Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:rat· 1

Frequent Co-Authors

Deborah M. HolsteiniD· 2 shared James Donald LechleiteriD· 2 shared Afaf SalibaiD· 1 shared Elizabeth S. FisheriD· 1 shared Gerard Nickel· 1 shared Jeremy J. Stubblefield· 1 shared JingMei Ren· 1 shared Jiwan KimiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersNeuroscience

Deborah M. HolsteinORCID

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2 papers

Recent·Most cited

NeuroscienceJournal of Cerebral Blood Flow & MetabolismPeer-reviewedApr 12, 2025

β-Hydroxybutyrate enhances brain metabolism in normoglycemia and hyperglycemia, providing cerebroprotection in a mouse stroke model.

Deborah M. Holstein, Afaf Saliba, Damian Lozano…·James Donald Lechleiter

This study shows that β-hydroxybutyrate reduces brain metabolic stress and infarct size in a mouse stroke model under hyperglycemic conditions.

11 citationstop 2%

mouseexperimental assay

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NeuroscienceFrontiers in StrokePeer-reviewedNov 22, 2022

Adenosine A1R/A3R Agonist AST-004 Reduces Brain Infarction in Mouse and Rat Models of Acute Ischemic Stroke

Elizabeth S. Fisher, Yanan Chen, Mikaela M. Sifuentes…·James Donald Lechleiter

This study shows AST-004, an A1R/A3R agonist, reduces brain infarction in mouse and rat stroke models, with efficacy dependent on A3R signaling and astrocyte mitochondrial metabolism.

8 citations

mouserat

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