Author

Lesley Seymour

Canadian Cancer Trials GroupORCID 0000-0001-8081-0799Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Armaghan SarvariD· 1 shared Auden Hafezi· 1 shared Damian YapiD· 1 shared Daniel LaiiD· 1 shared Dave W. CesconiD· 1 shared Elena ZaikovaiD· 1 shared Jay Tan· 1 shared John Frederick HiltoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Armaghan SarvarORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintApr 14, 2026

The UV potentiated mutational signature of clinical stage G-quadruplex binder CX5461.

Elena Zaikova, Damian Yap, Armaghan Sarvar…·Samuel A. J. R. Aparicio

The paper investigates the mutational signature of CX5461, a photosensitiser, when combined with UVA light, showing increased SNV burden only in co-exposed cells.

DOI 10.64898/2026.04.10.717570

humanwhole-genome sequencing

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