Author

Isabelle Vandernoot

Université Libre de BruxellesORCID 0000-0001-8084-7858Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:zebrafish· 3 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Achim Trubiroha· 3 shared Benoît HaerlingeniD· 3 shared Pierre GillotayiD· 3 shared Robert OpitziD· 3 shared Sabine CostagliolaiD· 3 shared Angelo MolinaroiD· 1 shared Meghna ShankariD· 1 shared Nicoletta Giusti· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 31 mutual co-author links

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3 shared papersDevelopmental Biology

Achim Trubiroha

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3 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedMay 12, 2023

Mesodermal FGF and BMP govern the multi-step thyroid specification

Benoît Haerlingen, Robert Opitz, Isabelle Vandernoot…·Sabine Costagliola

This study identifies the role of FGF and BMP signaling in thyroid progenitor specification in zebrafish embryos, showing FGF regulates Pax2a and BMP regulates both Pax2a and Nkx2.4b.

11 citations

zebrafishexperimental assay

𝕏 PostBluesky

Developmental BiologyThyroidPeer-reviewedAug 11, 2020

Enhanced canonical Wnt signaling during early zebrafish development perturbs the interaction of cardiac mesoderm and pharyngeal endoderm and causes thyroid specification defects

Isabelle Vandernoot, Benoît Haerlingen, Pierre Gillotay…·Sabine Costagliola

This study shows that enhanced Wnt signaling during zebrafish development disrupts cardiac mesoderm-endoderm interactions, leading to thyroid specification defects and cardiovascular abnormalities.

17 citations

zebrafishexperimental assay

𝕏 PostBluesky

Developmental BiologyThyroidPeer-reviewedSep 11, 2019

Small Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid Development

Benoît Haerlingen, Robert Opitz, Isabelle Vandernoot…·Sabine Costagliola

The paper identifies BMP and FGF signaling as key regulators of thyroid development in zebrafish embryos through small molecule screening and links these findings to conserved vertebrate mechanisms.

26 citations

zebrafishexperimental assay

𝕏 PostBluesky