Author

Irene Blasco-Machín

ORCID 0000-0001-8088-8318Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Esther BrosetiD· 2 shared Juan Martínez-OlivániD· 2 shared Alfonso Toro-CórdovaiD· 1 shared Ana M. SerranoiD· 1 shared Carlos MatuteiD· 1 shared David Luna-CerralboiD· 1 shared Fadi Hamdan· 1 shared Pierpaolo BruscoliniiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

Esther BrosetORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintSep 30, 2025

Enhancement of mRNA translation efficiency through 5'-UTR engineering

Esther Broset, Irene Blasco-Machín, Verónica Lampaya…·Juan Martínez-Oliván

This study enhances mRNA translation efficiency by engineering Kozak repeats in the 5'-UTR, showing improved expression in both cell culture and mice.

DOI 10.1101/2025.09.30.679448

humanmouse

𝕏 PostBluesky

Synthetic BiologyComputational and Structural Biotechnology JournalPeer-reviewedJan 1, 2025

CertPrime: a new oligonucleotide design tool for gene synthesis

David Luna-Cerralbo, Ana M. Serrano, Irene Blasco-Machín…·Pierpaolo Bruscolini

CertPrime improves oligonucleotide design by reducing melting temperature deviations and spurious dimer formation, enhancing gene synthesis efficiency.

2 citations

humanDNA methylation

𝕏 PostBluesky