Reconstitution of human fetal ovaries reveals niche requirements for primordial germ cell-like cell progression
Yolanda W. Chang, Marjolein Trimp, Talia van der Helm…·Susana M. Chuva de Sousa Lopes
This study shows that human primordial germ cell-like cells can mature in reconstituted human fetal ovaries and amnion-like cell aggregates, with SCF being crucial for hPGCLC survival.