Ioannis Moustakas

Loss of ABCA4 from photoreceptor discs triggers changes in glial cell homeostasis

This study uses hiPSC-derived retinal organoids to show that ABCA4 loss in photoreceptors disrupts glial cell homeostasis, suggesting a role for glial cells in Stargardt disease progression.

Characterization of the human fetal rete region by single cell transcriptional analysis of gonads and mesonephros/epididymis

The paper uses single-cell transcriptomics to study fetal rete testis development, identifying molecular markers and cell types in human gonads and mesonephros/epididymis.

Efficient and scalable generation of primordial germ cells in 2D culture using basement membrane extract overlay

This paper introduces a method to efficiently generate human primordial germ cell-like cells (hPGCLCs) in 2D culture using basement membrane extract overlay and low BMP4 concentration.