Olivia Lenoir

This study develops a mouse model of hypertensive emergency with multiorgan microvascular disease and identifies dysregulated VEGFA/sFlt-1 signaling as a key driver.

This study investigates how UBA1 mutations in VEXAS syndrome lead to monocyte dysfunction and inflammation through RIPK1-mediated cell death and impaired NF-κB signaling.

This study shows that blood-borne sphingosine 1-phosphate (S1P) maintains vascular resistance and cardiac function through albumin-S1P and myocyte S1PR signaling in mice.