BioengineeringbioRxivPreprint
Mineralized Tissue-Targeting Expression System for Local Control of Gene Expression
Jingyi Liu, Qinyuan Chen, Il‐Chul Yoon…·Kyle H. Vining
This paper develops a gene expression system targeting mineralized tissues using bisphosphonate lipids, demonstrating enhanced RNA delivery and local therapeutic effects in bone regeneration and inflammation.
DOI 10.1101/2025.11.25.690451