Junchao Xu

This paper develops nanodiscs for targeted delivery of an anti-inflammatory drug to macrophages in AAA, showing reduced disease progression in mice.

This study develops a combinatorial chemistry approach to create biodegradable ionizable lipids for efficient mRNA delivery and gene editing in vivo.

This paper develops a gene expression system targeting mineralized tissues using bisphosphonate lipids, demonstrating enhanced RNA delivery and local therapeutic effects in bone regeneration and inflammation.