Cancer BiologybioRxivPreprint
Cell-Permeable Morpholino Inhibits Programmed Death-Ligand 1 at mRNA Level and Potentiates Antitumor Immunity in Breast Cancer
Sudipta Sarkar, Ujjwal Ghosh, Subhamoy Pratihar, Surajit Sinha
This study develops a cell-permeable morpholino ASO targeting PD-L1 in breast cancer, which reduces PD-L1 expression and enhances antitumor immunity when combined with durvalumab.