Surajit Sinha

This study develops a cell-permeable morpholino ASO targeting PD-L1 in breast cancer, which reduces PD-L1 expression and enhances antitumor immunity when combined with durvalumab.

This paper introduces a method to control mRNA translation in vivo using photocaged morpholino oligonucleotides, enabling light-induced protein production and function studies.

This paper develops bioisosteric iboga analogs with improved antinociceptive and anxiolytic properties and reduced cardiotoxicity compared to natural iboga alkaloids.

This paper shows butyrate enhances B10 cell generation via the AUF1-IL-27 axis in IBD patients and mice, reducing inflammation.

The paper investigates how butyrate affects cholesterol levels through the AUF-1-Dicer-1-miR122 pathway in mice, showing that AUF-1 knockdown increases miR122 and reduces serum cholesterol.